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Cryogenic contrast-enhanced microCT enables nondestructive 3D quantitative histopathology of soft biological tissues

Cryogenic contrast-enhanced microCT enables nondestructive 3D quantitative histopathology of soft biological tissues Biological tissues comprise a spatiallycomplex structure, composition andorganization at the microscale, named the microstructure. Given the closestructure-function relationships in tissues, structural characterization isessential to fully understand the functioning of healthy and pathological tis-sues, as well as the impact of possible treatments. Here, we …

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Development and characterization of a rat brain metastatic tumor model by multiparametric magnetic resonance imaging and histomorphology

Development and characterization of a rat brain metastatic tumor model by multiparametric magnetic resonance imaging and histomorphology Abstract To facilitate the development of new brain metastasis (BM) treatment, an easy-to-use and clinically relevant animal model with imaging platform is needed. Rhabdomyosarcoma BM was induced in WAG/Rij rats. Post-implantation surveillance and characterizations were systematically performed with …

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Multiscale modelling of capillary imbibition in 3D_printed porous microfluidic channels

Multiscale modelling of capillary imbibition in 3D-printed porous microfluidic channels   Abstract 3D-printed porous microfluidics has been proposed to realize complex passive lab-on-chips. The performance of these devices depends on capillary flow design and control. To this end, a predictive multiscale model of capillary imbibition in porous channels obtained through powder-based 3D printing was developed. …

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The translaminar fracture toughness of high-performance polymer fibre composites and their carbon fibre hybrids

The translaminar fracture toughness of high-performance polymer fibre composites and their carbon fibre hybrids   Abstract The translaminar fracture toughness is a key property that governs the damage tolerance and notch sensitivity of fibre-reinforced composites. Compact tension tests were performed to investigate the translaminar fracture toughness of composites reinforced with three types of high-performance polymer …

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Exploiting the rapid solidification potential of laser powder bed fusion in high strength and crack-free Al-Cu-Mg-Mn-Zr alloys

Abstract This work describes a systematic alloy design strategy resulting in the development of a high strength aluminum alloy adopted for L-PBF. First, based on the composition of a reference Al-Cu-Mg alloy, three Al-Cu-Mg-Mn-Zr-based alloys were investigated using computational thermodynamic tools. Subsequently, the L-PBF processing behavior, microstructure, and concomitant mechanical properties of the L-PBF-fabricated alloys …

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Model for calcite spherulite formation in organic, clay-rich, lacustrine carbonate shales

Research paper Model for calcite spherulite formation in organic, clay-rich, lacustrine carbonate shales (Barbalha Formation, Aptian, Araripe Basin, NE Brazil) Abstract The formation of carbonate spherulites, recognized as part of the South-Atlantic Pre-Salt reservoir rocks, remains enigmatic. Well-chosen analogues provide insights into depositional and diagenetic conditions and the biotic versus abiotic processes that might influence or …

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Digital volume correlation for meso/micro in-situ damage analysis in carbon fiber reinforced composites

Digital volume correlation for meso/micro in-situ damage analysis in carbon fiber reinforced composites   Abstract Recently, in-situ X-ray Computed Tomography (CT) has shown its potential for 3D damage analysis in composite materials. However, the characterization of damage in X-ray tomograms is not always straightforward, and it requires post-processing of the 3D images. In this study, …

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Community mask research

Respiratory viruses, like the coronavirus, spread between humans via direct contact, respiratory droplets and fine-particle aerosols (see figure below). Since the outbreak of the COVID-19 pandemic, demand and prices for personal protective equipment, such as medical face masks, has been up to 100 and 20 times higher than normal, respectively. Shortages of medical masks has …

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