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Accuracy of photon-counting computed tomography for the measurement of bone quality in the knee

Abstract Visualization and quantification of bone microarchitecture in the human knee allows gaining insight into normal bone structure, and into the structural changes occurring in the onset and progression of bone diseases such as osteoporosis and osteoarthritis. However, current imaging modalities have limitations in capturing the intricacies of bone microarchitecture. Photon counting computed tomography (PCCT) …

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UV-Curing Assisted Direct Ink Writing of Dense, Crack-Free, and High-Performance Zirconia-Based Composites With Aligned Alumina Platelets

Abstract Additive manufacturing (AM) of high-performance structural ceramic components with comparative strength and toughness as conventionally manufactured ceramics remains challenging. Here, a UV-curing approach is integrated in direct ink writing (DIW), taking advantage from DIW to enable an easy use of high solid-loading pastes and multi-layered materials with compositional changes; while, avoiding drying problems. UV-curable …

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3D printing of an iron-rich slag based hybrid mortar. A durable, sustainable and cost-competitive product?

Abstract Automation through 3D printing can be a possible technological breakthrough in construction. However, the carbon footprint is not necessarily reduced as the print formulations consist of more ordinary Portland cement (OPC) compared to conventional high-performance mortar. In this study, a hybrid mortar with minor amount of OPC and mainly Fe-rich, low-Ca slag is used for printing several structures, …

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Ultrasonication optimisation and microstructural characterisation for 3D nanoparticle dispersion in thermoplastic and thermosetting polymers

Abstract 3D nanoparticles are important as reinforcing or functional phase in polymer composite materials; however, an optimised deagglomeration and uniform distribution of these particles is required to fully exploit their nanoscale properties. Classical dispersion methods like shear mixing have proven insufficient, and high-energy ultrasonication, as the preferred deagglomeration method, requires a challenging system-specific optimisation procedure. …

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Cryogenic contrast-enhanced microCT enables nondestructive 3D quantitative histopathology of soft biological tissues

Cryogenic contrast-enhanced microCT enables nondestructive 3D quantitative histopathology of soft biological tissues Biological tissues comprise a spatiallycomplex structure, composition andorganization at the microscale, named the microstructure. Given the closestructure-function relationships in tissues, structural characterization isessential to fully understand the functioning of healthy and pathological tis-sues, as well as the impact of possible treatments. Here, we …

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Development and characterization of a rat brain metastatic tumor model by multiparametric magnetic resonance imaging and histomorphology

Development and characterization of a rat brain metastatic tumor model by multiparametric magnetic resonance imaging and histomorphology Abstract To facilitate the development of new brain metastasis (BM) treatment, an easy-to-use and clinically relevant animal model with imaging platform is needed. Rhabdomyosarcoma BM was induced in WAG/Rij rats. Post-implantation surveillance and characterizations were systematically performed with …

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Multiscale modelling of capillary imbibition in 3D_printed porous microfluidic channels

Multiscale modelling of capillary imbibition in 3D-printed porous microfluidic channels   Abstract 3D-printed porous microfluidics has been proposed to realize complex passive lab-on-chips. The performance of these devices depends on capillary flow design and control. To this end, a predictive multiscale model of capillary imbibition in porous channels obtained through powder-based 3D printing was developed. …

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The translaminar fracture toughness of high-performance polymer fibre composites and their carbon fibre hybrids

The translaminar fracture toughness of high-performance polymer fibre composites and their carbon fibre hybrids   Abstract The translaminar fracture toughness is a key property that governs the damage tolerance and notch sensitivity of fibre-reinforced composites. Compact tension tests were performed to investigate the translaminar fracture toughness of composites reinforced with three types of high-performance polymer …

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